Real Free Market: “Clueless people get obsessed with languages and frameworks. No matter what language and framework you use, you have to write your application code. If you use a fancy framework, then you have to write framework-compliant code in addition to your programâ€™s code. With node.js, youâ€™re fiddling around with callback functions and manually managing timing, instead of letting Apache and the OS do it for you.”
It looks like node.js is good, for simple apps. If you want to get serious, find a bigger hammer.